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    GHRP-2

    CompoundableApproved in Japan as a diagnostic agent for GH deficiency; not FDA-approved in the US.

    Growth Hormone Releasing Peptide-2

    Description

    A growth hormone releasing peptide that stimulates natural GH secretion. Works synergistically with GHRH analogues for enhanced growth hormone release.

    Dose:100-300 mcg
    Frequency:1-3 times daily
    Administration Method: SQ
    CategoryGH Secretagogue
    Half-LifeApproximately 20-30 minutes.

    Overview

    GHRP-2 is a potent GH secretagogue used in research and as a GH-deficiency diagnostic. It is typically dosed by subcutaneous injection and is commonly studied alongside GHRH analogs for synergistic GH release.

    Mechanism of Action

    GHRP-2 (pralmorelin) is a synthetic hexapeptide agonist of the ghrelin receptor (GHS-R1a). It stimulates pulsatile growth hormone release from the anterior pituitary and can transiently elevate cortisol and prolactin.

    Benefits

    • •Growth hormone release
    • •Muscle growth
    • •Fat loss
    • •Improved sleep
    • •Anti-aging
    • •Appetite stimulation

    Reported Side Effects

    • •increased appetite
    • •water retention
    • •transient cortisol and prolactin elevation

    Safety Notes

    Not FDA-approved in the US. Elevations in cortisol and prolactin can occur.

    Scientific References

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