PepCalcs
    Back to Library

    IGF-1 LR3

    Research Use OnlyNot FDA-approved; experimental outside research or wellness clinics.

    Insulin-like Growth Factor-1 Long R3

    Description

    An extended form of IGF-1 with increased half-life and potency. Promotes muscle growth and recovery with enhanced anabolic effects.

    Dose:50 mcg
    Frequency:10 days on, 4 weeks off
    Administration Method: SQ
    CategoryMuscle Building
    Half-Life20-30 hours

    Overview

    IGF-1 LR3 is an engineered 83-amino-acid protein with an arginine substitution at the third position and a 13-amino-acid N-terminal extension. This structure provides enhanced stability and potency vs. natural IGF-1, allowing sustained activity.

    Mechanism of Action

    IGF-1 LR3 functions by binding to cell receptors in muscle tissue, triggering a cascade of biological responses. Its modified structure allows it to bypass typical protein binding. It enhances glucose transport, activates protein synthesis, stimulates cell communication pathways for growth, and regulates metabolism.

    Benefits

    • •Muscle growth
    • •Recovery
    • •Fat loss
    • •Protein synthesis
    • •Cell proliferation
    • •Anabolic effects

    Dosing Notes

    Administration is typically subcutaneous, with careful dosing and cycling to avoid receptor desensitization and adverse metabolic effects.

    Reported Side Effects

    • •hypoglycemia
    • •insulin resistance
    • •fluid retention
    • •potential mitogenic effects

    Safety Notes

    Medical supervision is essential, particularly for those at risk for metabolic or oncologic conditions. IGF-1 LR3 is banned in sports.

    Scientific References

    Related Muscle Building Peptides