Semaglutide Dosage Calculator

Semaglutide research vials are typically 2 mg, 3 mg, 5 mg, or 10 mg of lyophilized peptide. Because protocols titrate weekly through 0.25 mg → 0.5 mg → 1 mg → 1.7 mg → 2.4 mg, you want a reconstitution volume that makes every step in the titration draw as a clean number of insulin units.

Enter the mg in your vial, the bacteriostatic water you'll add, and the current step of your titration. The calculator returns the mg/mL concentration, the mL to draw, and the equivalent U-100 insulin units. Save each step and the calculator will keep track of how many doses remain in the vial.

Example: a 5 mg semaglutide vial reconstituted with 2 mL of bacteriostatic water yields 2.5 mg/mL. A 0.25 mg dose is 0.1 mL (10 units), a 0.5 mg dose is 0.2 mL (20 units), a 1 mg dose is 0.4 mL (40 units), and so on — a very readable titration.