Tirzepatide Reconstitution Calculator
Titrate a tirzepatide vial from 2.5 mg to 15 mg with clean insulin-unit doses.
Open the calculator
Pre-filled with Tirzepatide defaults — adjust vial size, water volume, and dose to your protocol.
About the Tirzepatide Reconstitution Calculator
Tirzepatide research vials are commonly 5 mg, 10 mg, 15 mg, 20 mg, 30 mg, or 60 mg of lyophilized peptide. Titration protocols step through 2.5 mg → 5 mg → 7.5 mg → 10 mg → 12.5 mg → 15 mg weekly, so the goal of reconstitution is to pick a bacteriostatic water volume where each step draws as a clean insulin-unit number.
Enter your vial strength, water volume, and current titration dose below. The calculator returns the mg/mL concentration, the mL to draw, and the U-100 insulin units, plus a suggested "optimal" volume that keeps doses on whole-unit marks and minimizes waste.
Example: a 30 mg tirzepatide vial reconstituted with 3 mL of bacteriostatic water yields 10 mg/mL. A 2.5 mg dose is 0.25 mL (25 units), a 5 mg dose is 0.5 mL (50 units), and a 10 mg dose is 1 mL (100 units) — one syringe, one draw, at every step of the titration.
Quick reference
- Typical vial sizes
- 5 mg · 10 mg · 15 mg · 20 mg · 30 mg · 60 mg
- Typical research dose range
- 2.5 mg to 15 mg weekly (titrated)
How to prepare Tirzepatide
- Draw the intended volume of bacteriostatic water into a sterile syringe.
- Slowly inject the water down the inside wall of the tirzepatide vial — never directly onto the lyophilized powder.
- Gently swirl (do not shake) until the powder is fully dissolved and the solution is clear.
- Store the reconstituted vial refrigerated at 2–8°C and use within the peptide's stability window.
- Use the concentration and dose volume calculated above to draw each research dose into an insulin syringe.
Frequently asked questions
How do I reconstitute tirzepatide?
Add bacteriostatic water to the tirzepatide vial using the volume the calculator recommends for your desired concentration. Slowly inject the water down the side of the vial, swirl gently, and store the vial refrigerated.
What bacteriostatic water volume should I use for tirzepatide?
Common choices are 1 mL, 2 mL, or 3 mL of bacteriostatic water. The right volume depends on your vial strength and target dose — use the calculator above to get a concentration that lets you draw your dose in whole insulin units.
What is a typical research dose range for tirzepatide?
Reported research dose ranges for tirzepatide are 2.5 mg to 15 mg weekly, titrated slowly. Always verify against current literature — this tool is for research reference only, not medical advice.
How long is tirzepatide stable after reconstitution?
Once reconstituted with bacteriostatic water and stored refrigerated (2–8°C), most peptides remain stable for roughly 28–30 days. Check the specific stability data for tirzepatide for your batch.
Can I use this tirzepatide calculator with any insulin syringe?
Yes. The calculator supports U-100 syringes in 30, 50, and 100-unit capacities and shows both the mL dose volume and the equivalent insulin units for whichever syringe you choose.
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